Optometric Management Special Edition

2015

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S P E C I A L E D I T I O N 2 0 1 5 • O P T O M E T R I C M A N A G E M E N T . C O M DAVID RUSTON, F.C.OPTOM, DIP.C.L.P., F.A.A.O., is director, Global Professional Affairs for Johnson & Johnson Vision Care Compa- nies in London, UK. Visit tinyurl.com/OMcomment to comment on this article. REFERENCES 1. Omali NB, Subbaraman LN, Coles-Brennan C, Fadli Z, Jones LW. Biological and Clinical Implications of Lysozyme Deposition on Soft Contact Lenses. Optometry and Vision Science, Vol. 92, No. 7, July 2015. 2. Leahy CD et al. Initial in vivo tear protein deposition on individual hydrogel contact lenses. Optom Vis Sci 1990: 67: 7: 504-511. 3. Zhao Z et al. Proteomic analysis of protein deposits on worn daily wear silicone hydrogel contact lenses. Mol Vis 2008: 14: 2016-2024. 4. McCanna D, Oh S, Seo J et al. Effect of denatured lyso- zyme on human corneal epithelial cells. IOVS 2015; 56:ARVO E-abstract 3511. 5. Fleming A. On a remarkable bacteriolytic ele- ment found in tissues and secretions. Proc Roy Soc 1922; 43:306Y17. 6. Leitch EC, Willcox MD. Lactoferrin increases the sus- ceptibility of S. epidermidis bioflms to lysozyme and vanco- mycin. Curr Eye Res 1999;19:12Y9. 7. Okada E, Matsuda T, Yokoyama T, Okuda K. Lysozyme penetration in group IV soft contact lenses. Eye Contact Lens 2006;32:174Y7. 8. Jones L, Senchyna M, Glasier MA, Schickler J, Forbes I, Louie D, May C. Lysozyme and lipid deposition on silicone hydrogel contact lens materials. Eye Contact Lens 2003;29:S75Y9. FE ATURE PROTEIN DEPOSITION 23 A DIVERSE PATIENT BASE Q: WITH SO MANY LENSES TO CHOOSE FROM, WHAT IS THE ROLE OF 1-DAY ACUVUE MOIST BRAND IN YOUR PRACTICE? Charles Clayton, OD: I can count on 1-DAY ACUVUE MOIST for all my patients that need a lens for their discomfort-prone eyes and that blocks at least 97% UVB and 81% UVA. † * Te platform also makes it easy for me to ft a wide range of pa- tients — even if the patient has astigmatism or presbyopia. ADDRESSING CHALLENGES Q: HOW DOES THE LENS HELP YOU ADDRESS CONTACT LENS COMFORT CHALLENGES, SUCH AS FEELINGS OF DRYNESS AND IRRITATION? Dr. Clayton: With this lens, the PVP wetting agent is locked into the lens using LACREON Technology — it's not transient. Te moisture lasts, which gives you high success from morning to night. Te lens also features an INFINITY EDGE design that helps minimize mechanical irritation throughout the day. EFFECTS OF LYSOZYME Q: WHAT IS YOUR OPINION ON THE EFFECTS OF LYSOZYME ON THE ETAFILCON A MATERIAL? Dr. Clayton: Much like fats, proteins have a bad reputation. But as with fat, there are good forms and bad forms. Lysozyme plays a positive role in the tear flm. As long as it doesn't break down, it's benefcial, and another reason I choose the 1-DAY ACUVUE MOIST Brand. RELAYING BENEFITS TO PATIENTS Q: HOW DO YOU RELAY THOSE BENEFITS TO PATIENTS? Dr. Clayton: Some patients want a technical explanation and others don't. Generally, I explain that 1-DAY ACUVUE MOIST is a gentle lens that helps keep some of the good components of the tear flm in their happy, natural form § and it has built-in moisture from morning to night. CHARLES CL AYTON, O.D., is in private practice at Bellevue Vision Clinic in Bellevue, WA. He received compensation from Johnson & Johnson Vision Care, Inc. for his time spent for this article. Practitioner Experience A Q&A; with Dr. Charles Clayton, O.D., about how he incorporates 1-DAY ACUVUE MOIST Brand Contact Lenses into his practice. § Data on fle, 2014. Based on in-vitro data; clinical studies have not been done directly linking differences in lysozyme profle with specifc clinical benefts †Helps protect against transmission of harmful UV radiation through the cornea and into the eye. *WARNING: UV-absorbing contact lenses are NOT substitutes for protective UV-absorbing eyewear, such as UV-absorbing goggles or sun- glasses, because they do not completely cover the eye and surrounding area. You should con- tinue to use UV-absorbing eyewear as directed. NOTE: Long-term exposure to UV radiation is one of the risk factors associated with cataracts. Exposure is based on a number of factors such as environmental conditions (altitude, geography, cloud cover) and personal factors (extent and nature of outdoor activities). UV-blocking contact lenses help provide protection against harmful UV radiation. However, clinical studies have not yet been done to demonstrate that wearing UV-block- ing contact lenses reduces the risk of developing cataracts or other ocular disorders. Consult your eye care practitioner for more information. See page 4 for more important prescribing information.

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