Optometric Management Special Edition

2015

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S P E C I A L E D I T I O N 2 0 1 5 • O P T O M E T R I C M A N A G E M E N T . C O M 19 HydraLuxe Technology that gives them such robust per- formance in tribological testing? Several aspects of the lens may be responsible. First, HydraLuxe Technology works continuously throughout the day to lubricate and moistur- ize the lens. On the eye, the lens supports the tear flm be- cause the lens is like the tear flm. In addition, the lens is extremely smooth. Tis has been demonstrated via transmission electron microscopy (TEM), which enables examination of contact lens surfaces under high magnifcation (i.e., sub-micron dimensions), allowing precise visualization of the surface and bulk or matrix of a material (Figure 3). 5 Tis has also been corrob- orated by atomic force microscopy (AFM) measurements (not shown). Additionally, these lenses also have a unique tear- infused design with an enhanced network of tear-like mol- ecules and highly breathable silicone that integrates with the patient's own tear flm. Tis uniform tear-like network exists throughout the en- tire lens; it is not just a surface coating. Te data shows that the low frictional energy profle of the lens lasts throughout the day. PROPER MOISTURE AND LUBRICATION Innovation leads to advancements and, ultimately, to patient benefts. ACUVUE OASYS 1-Day with HydraLuxe Technology lenses have demonstrated consis- tently low frictional energies through time when measured using a physiologically relevant methodology. Perhaps this is because the tear-infused design integrates key tear-like components — not just water — to moisturize and lubri- cate the lens throughout the day. In addition, the lenses are exceptionally smooth — as demonstrated by TEM and corroborated by AFM — and rather than employing a thin surface coating, they maintain a uniform, tear-like network throughout the entire lens. Clinical studies will deter- mine whether these lenses deliver the on-eye perfor- mance that their impressively low and stable frictional energy predicts. OM REFERENCES 1. Nichols JJ, Willcox MDP, Bron AJ, et al. The TFOS International Workshop on Contact Lens Discomfort: Executive Summary. Invest Ophthalmol Vis Sci. 2013;54:TFOS7-TFOS13. 2. Roba M, Duncan EG, Hill GA, Spencer ND, Tosatti SPG. Friction measure- ments on contact lenses in their operating environment. Tribol Lett. 2011;44: 387-97. 3. Coles-Brennan C, Brennan N. Coeffcient of Friction and Soft Contact Lens Comfort. Presented at American Academy of Optometry Annual Meeting. Phoenix AZ, October 24, 2012. Poster 70. 4. Dumbleton K, Woods CA, Jones LW, Fonn D. The impact of contempo- rary contact lenses on contact lens discontinuation. Eye Contact Lens. 2013 Jan;39(1):93-9. 5. Subbaraman LN, Jones LW. Measuring Friction and Lubricity of Soft Contact Lenses: A Review. Contact Lens Spectrum. June 2013. Accessed August 28, 2015 at http://www.clspectrum.com/articleviewer.aspx?articleID=108560 CHARLES SCALES, Ph.D., is principal scientist for Johnson & Johnson Vision Care, Inc., in Jacksonville, Fla. BRIAN PALL, O.D., M.S., F.A.A.O. is senior principal research optometrist, Johnson & Johnson Vision Care, Inc. To comment on this article, visit tinyurl.com/ OMcomment. 0 5 10 15 20 0 200 400 600 ACUVUE OASYS ® with HydraLuxe T M 95 % CI ACUVUE OASYS ® with HydraLuxe T M 95 % PI ACUVUE OASYS ® with HydraLuxe T M Inc rea s ing F ric tiona l E nergy (nJ ) C y c ling T ime in T ea r-L ik e F luid (H ours ) 1 um Lens Surface Lens Bulk ACUVUE OASYS® with HydraLuxe™ Technology Figure 2: Frictional energy of ACUVUE OASYS 1-Day with HydraLuxe Technology, measured by a microtribometer. Note the low and highly reproducible values recorded (95% confdence and prediction intervals are shown). Figure 3: Transmission Electron Micrograph (TEM) of ACUVUE OASYS 1-Day with HydraLuxe Technology show- ing extremely smooth surface and uniform composition throughout lens matrix. Please see page 4 for more important prescribing information. FE ATURE HOW HARD ARE YOUR PATIENTS' E YE WORKING?

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